Hyaluronate Targeted Solid Lipid Nanoparticles of Etoposide: Optimization and In Vitro Characterization

Table 3

Particle size and polydispersity index (PdI) of nontargeted and HA targeted SLNs (𝑛=3).

Formulation code	Particle size (nm) ± SD		Polydispersity index (PdI) ± SD
	Nontargeted	HA targeted	Nontargeted	HA targeted
C2L1.5DO20	400.3±29.5	620.9±48.3	0.309±0.035	0.493±0.053
C1L3SO20	211.8±22.3	406.3±36.2	0.226±0.038	0.342±0.065
C1L3DO20	525.1±44.9	712.4±85.9	0.602±0.041	0.812±0.069
C2L3DO10	336.2±36.2	488.2±72.3	0.485±0.028	0.764±0.058
C1L3SO10	219.3±33.1	409.1±43.7	0.294±0.047	0.369±0.061
C1L1.5SO10	187.3±14.5	411.6±28.1	0.165±0.023	0.287±0.044
C1L1.5DO20	493.5±38.3	790.5±66.4	0.343±0.033	0.674±0.049
C2L1.5SO20	299.9±45.7	507.3±61.8	0.317±0.061	0.358±0.082
C1L1.5DO10	528.5±61.7	804.7±79.5	0.584±0.052	0.719±0.078
C2L3DO20	300.2±47.8	452.6±69.1	0.407±0.062	0.790±0.088
C2L3SO10	250.4±49.7	395.6±57.1	0.361±0.064	0.512±0.073
C2L1.5SO10	214.1±51.2	427.2±71.7	0.426±0.053	0.548±0.085