Photothermal Therapy Using Gold Nanorods and Near-Infrared Light in a Murine Melanoma Model Increases Survival and Decreases Tumor Volume

Figure 3

Photothermal properties of GNRs in animal tissue models. (a) Graph showing temperature increase over time for different combinations of GNR concentrations and tumor depths. OD 1 was used for superficial tumor models (0 cm deep), OD 10 was used for 0.5 cm deep tumor models, and OD 12 was used for 1.0 cm deep tumor models in order to reach target ablation temperatures. All models were exposed to 3.5 W/cm² of NIR light. (b) and (c) Thermographic images of GNR filled “X” in animal tissue models, before ((b), t = 0) and after ((c), t = 120 s) NIR light exposure (OD 3.3, 2.2 W/cm²).

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