Development, Characterization, and Evaluation of PSMA-Targeted Glycol Chitosan Micelles for Prostate Cancer Therapy

Table 1

Physicochemical properties of drug-free and DOX-loaded micelles.

Sample	DOX/carrier^a	Size (nm)^b	PDI^c	LC (%)^d	EE (%)^e
CHGC	—	228 ± 19.1	0.283 ± 0.056	—	—
PCP-CHGC	—	246 ± 20.4	0.276 ± 0.063	—	—
DOX-CHGC	1.5/10	274 ± 23.0	0.234 ± 0.053	10.5 ± 0.73	81.8 ± 9.34
DOX-PCP-CHGC	1.5/10	293 ± 22.5	0.289 ± 0.087	11.4 ± 0.48	85.8 ± 4.07

The ratio of DOX to carrier, based on feed amount (mg/mg). ^bMeasured by dynamic light scattering. ^cPolydispersity index. ^dLoading content. ^eEncapsulation efficiency. The results represent the mean ± SD ().