Scaffolding Biomaterials for Cartilage Regeneration

Table 1

Physical modification on scaffolds.

Scaffolds	Methods	Effect	References
Cartilage-derived matrix scaffolds	Dehydrothermal treatment; ultraviolet light irradiation	Make chondrocytes to produce higher glycosaminoglycan and collagen contents and support cell attachment	Rowland et al., 2013 [16]
Collagen type-I gel	Compression and filtration	Improve the biomechanical and biochemical properties of scaffold	Mueller-Rath et al., 2010 [17]
Alginate scaffold	Microfluidic technology	Enable the scaffold to have a regular interconnected porous structure and high porosity	Wang et al., 2011 [18]
PLGA	Scaffold orientation	Promote cell migration and improve the mechanical property of engineered cartilage	Zhang et al., 2012 [19]
Cartilage extracellular matrix	Scaffold orientation	Enhance the biomechanical property of engineered cartilage	Jia, et al., 2012 [20]

PLGA: poly(lactic-co-glycolic acid).