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Journal of Nanomaterials
Volume 2014 (2014), Article ID 507273, 19 pages
http://dx.doi.org/10.1155/2014/507273
Review Article

Applications of Dendrimers in Drug Delivery Agents, Diagnosis, Therapy, and Detection

1Centro de Investigación y Desarrollo Tecnológico en Electroquímica S.C., Parque Tecnológico Querétaro s/n, Sanfandila, 76703 Pedro Escobedo, QRO, Mexico
2Medicine Faculty, Universidad Autónoma de Querétaro, Fraccionamiento Prados de la Capilla, 76176 Santiago de Querétaro, QRO, Mexico

Received 11 November 2013; Accepted 7 February 2014; Published 15 April 2014

Academic Editor: Mustafa O. Guler

Copyright © 2014 B. Noriega-Luna et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

In recent years, the application of dendrimers in biomedicine attracted much attention from scientists. Dendrimers are interesting for biomedical applications because of their characteristics, including: a hyperbranching, well-defined globular structures, excellent structural uniformity, multivalency, variable chemical composition, and high biological compatibility. In particular, the three-dimensional architecture of dendrimers can incorporate a variety of biologically active agents to form biologically active conjugates. This review of dendrimers focuses on their use as protein mimics, drug delivery agents, anticancer and antiviral therapeutics, and in biomedical diagnostic applications such as chemically modified electrodes.