Applications of Dendrimers in Drug Delivery Agents, Diagnosis, Therapy, and Detection

Table 1

Some properties calculated to PAMAM dendrimers by generation [4, 6, 8].

Generation	Molecular weight^a	Diameter (Å)^b	Functional groups
0	517	15	4
1	1 430	22	8
2	3 256	29	16
3	6 909	36	32
4	14 215	45	64
5	28 826	54	128
6	58 048	67	256
7	116 493	81	512
8	233 383	97	1 024
9	467 162	114	2 048
10	934 720	135	4 096

 ^aThe molecular weight is based on an ideal structure of the dendrimer.
^bMolecular dimensions were determined by size exclusion chromatography.