Sustained Release and Cytotoxicity Evaluation of Carbon Nanotube-Mediated Drug Delivery System for Betulinic Acid

<table>Proposed reaction scheme for the functionalization of BA molecules onto the f-SWCNTs nanocarrier via <svg height="6.42315pt" id="M9" style="vertical-align:-0.2129903pt" version="1.1" viewbox="-0.0498162 -6.21016 21.0148 6.42315" width="21.0148pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0135,0,0,-0.0135,0,0)"><path d="M574 449L545 460C526 432 516 430 487 430C404 430 311 435 226 435C104 435 56 379 25 341L43 318C81 354 121 372 181 372C161 246 87 53 23 3L30 -12C48 -12 88 -4 113 11C157 75 207 248 232 371L386 367L326 109C321 86 318 66 318 50C318 4 339 -12 366 -12C410 -12 461 21 505 69L492 96C467 79 434 60 418 60C406 60 400 78 411 147C422 217 439 300 457 366C487 366 524 367 536 370C547 385 558 408 574 449Z" id="g113-238"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="591" vert-adv-y="591"></glyph.data></g><g transform="matrix(.0135,0,0,-0.0135,8.008,0)"><path d="M300 253H71L57 198H286L300 253Z" id="g190-46"></path><glyph.data ascent="989" descent="-360" horiz-adv-x="356" vert-adv-y="356"></glyph.data></g><g transform="matrix(.0135,0,0,-0.0135,12.85,0)"><path d="M574 449L545 460C526 432 516 430 487 430C404 430 311 435 226 435C104 435 56 379 25 341L43 318C81 354 121 372 181 372C161 246 87 53 23 3L30 -12C48 -12 88 -4 113 11C157 75 207 248 232 371L386 367L326 109C321 86 318 66 318 50C318 4 339 -12 366 -12C410 -12 461 21 505 69L492 96C467 79 434 60 418 60C406 60 400 78 411 147C422 217 439 300 457 366C487 366 524 367 536 370C547 385 558 408 574 449Z" id="g113-238"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="591" vert-adv-y="591"></glyph.data></g></svg> stacking interaction.</table>

Journal of Nanomaterials

sch1

Scheme 1

Scheme 1: Sustained Release and Cytotoxicity Evaluation of Carbon Nanotube-Mediated Drug Delivery System for Betulinic Acid 