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Journal of Nanomaterials
Volume 2014 (2014), Article ID 967295, 8 pages
http://dx.doi.org/10.1155/2014/967295
Research Article

Coaxial Electrospinning with Mixed Solvents: From Flat to Round Eudragit L100 Nanofibers for Better Colon-Targeted Sustained Drug Release Profiles

1School of Materials Science & Engineering, University of Shanghai for Science and Technology, 516 Jungong Road, Yangpu District, Shanghai 200093, China
2School of Environment and Architecture, University of Shanghai for Science and Technology, Shanghai 200093, China

Received 6 December 2013; Revised 26 January 2014; Accepted 4 March 2014; Published 27 March 2014

Academic Editor: Aihua He

Copyright © 2014 Deng-Guang Yu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Mitragotri and J. Lahann, “Physical approaches to biomaterial design,” Nature Materials, vol. 8, no. 1, pp. 15–23, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. T. Lin and X. Wang, Encyclopedia of Nanoscience and Nanotechnology, Edited by H. S. Nalwa, American Scientific, Los Angeles, Calif, USA, 2nd edition, 2011.
  3. N. Vitchuli, Q. Shi, J. Nowak et al., “Atmospheric plasma application to improve adhesion of electrospun nanofibers onto protective fabric,” Journal of Adhesion Science and Technology, vol. 27, no. 8, pp. 924–938, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. J. Fang, H. Niu, H. Wang, X. Wang, and T. Lin, “Enhanced mechanical energy harvesting using needleless electrospun poly(vinylidene fluoride) nanofibre web,” Energy & Environmental Science, vol. 6, no. 7, pp. 2196–2202, 2013. View at Publisher · View at Google Scholar
  5. J. Fang, X. Wang, and T. Lin, “Nanofibrous p-n junction and its rectifying characteristics,” Journal of Nanomaterials, vol. 2013, Article ID 758395, 7 pages, 2013. View at Publisher · View at Google Scholar
  6. Y. Li, B. Guo, L. Ji et al., “Structure control and performance improvement of carbon nanofibers containing a dispersion of silicon nanoparticles for energy storage,” Carbon, vol. 51, pp. 185–194, 2013. View at Publisher · View at Google Scholar
  7. X.-Y. Li, X. Wang, D.-G. Yu et al., “Electrospun borneol-PVP nanocomposites,” Journal of Nanomaterials, vol. 2012, Article ID 731382, 8 pages, 2012. View at Publisher · View at Google Scholar
  8. D.-G. Yu, W. Chian, X. Wang, X.-Y. Li, Y. Li, and Y.-Z. Liao, “Linear drug release membrane prepared by a modified coaxial electrospinning process,” Journal of Membrane Sciences, vol. 428, no. 2, pp. 150–156, 2013. View at Publisher · View at Google Scholar
  9. D.-G. Yu, X.-Y. Li, X. Wang, W. Chian, Y.-Z. Liao, and Y. Li, “Zero-order drug release cellulose acetate nanofibers prepared using coaxial electrospinning,” Cellulose, vol. 20, no. 1, pp. 379–389, 2013. View at Publisher · View at Google Scholar
  10. D. G. Yu, X. Wang, X. Y. Li, W. Chian, Y. Li, and Y. Z. Liao, “Electrospun biphasic drug release polyvinylpyrrolidone/ethyl cellulose core/shell nanofibers,” Acta Biomaterialia, vol. 9, no. 3, pp. 5665–5672, 2013. View at Publisher · View at Google Scholar
  11. D.-G. Yu, G. R. Williams, X.. Wang, X. K. Liu, H. L. Li, and S. W. A. Bligh, “Coaxial electrospinning using a concentric Teflon spinneret to prepare biphasic-release nanofibers of helicid,” RSC Advances, vol. 3, no. 39, pp. 17775–17783, 2013. View at Publisher · View at Google Scholar
  12. K.-H. Roh, D. C. Martin, and J. Lahann, “Biphasic Janus particles with nanoscale anisotropy,” Nature Materials, vol. 4, no. 10, pp. 759–763, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Agarwal, A. Greiner, and J. H. Wendorff, “Functional materials by electrospinning of polymers,” Progress in Polymer Science, vol. 38, no. 6, pp. 963–991, 2013. View at Publisher · View at Google Scholar
  14. C. J. Luo, S. D. Stoyanov, E. Stride, E. Pelan, and M. Edirisinghe, “Electrospinning versus fibre production methods: from specifics to technological convergence,” Chemistry Society Reviews, vol. 41, no. 13, pp. 4708–4735, 2012. View at Publisher · View at Google Scholar
  15. A. K. Moghe and B. S. Gupta, “Co-axial electrospinning for nanofiber structures: preparation and applications,” Polymer Reviews, vol. 48, no. 2, pp. 353–377, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. D.-G. Yu, L.-M. Zhu, C. Branford-White, S. W. A. Bligh, and K. N. White, “Coaxial electrospinning with organic solvent for controlling the size of self-assembled nanoparticles,” Chemical Communications, vol. 47, no. 4, pp. 1216–1218, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. D.-G. Yu, C. J. Branford-White, N. P. Chatterton et al., “Electrospinning of concentrated polymer solutions,” Macromolecules, vol. 43, no. 24, pp. 10743–10746, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. D.-G. Yu, C. Branford-White, S. W. A. Bligh, K. White, N. P. Chatterton, and L.-M. Zhu, “Improving polymer nanofiber quality using a modified co-axial electrospinning process,” Macromolecular Rapid Communications, vol. 32, no. 9-10, pp. 744–750, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. D.-G. Yu, G. R. Williams, X. Wang, X.-K. Liu, H.-L. Li, and S. W. A. Bligh, “Dual drug release nanocomposites prepared using a combination of electrospraying and electrospinning,” RSC Advances, vol. 3, no. 14, pp. 4652–4658, 2013. View at Publisher · View at Google Scholar
  20. X.-X. Shen, D.-G. Yu, L.-M. Zhu, C. Branford-White, K. White, and N. P. Chatterton, “Electrospun diclofenac sodium loaded Eudragit L 100–55 nanofibers for colon-targeted drug delivery,” International Journal of Pharmaceutics, vol. 408, no. 1-2, pp. 200–207, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. D.-G. Yu, J.-H. Yu, L. Chen, G. R. Williams, and X. Wang, “Modified coaxial electrospinning for the preparation of high-quality ketoprofen-loaded cellulose acetate nanofibers,” Carbohydrate Polymers, vol. 90, no. 2, pp. 1016–1023, 2012. View at Publisher · View at Google Scholar
  22. N. A. Peppas, “Analysis of Fickian and non-Fickian drug release from polymers,” Pharmaceutica Acta Helvetiae, vol. 60, no. 4, pp. 110–111, 1985. View at Google Scholar · View at Scopus