Impact of Silver and Iron Nanoparticle Exposure on Cholesterol Uptake by Macrophages

Figure 5

Representative enhanced darkfield images of macrophages exposed to 20 nm AgNPs, 110 nm AgNPs, or 20 nm Fe₃O₄ NPs visually demonstrating NP uptake. Images demonstrate macrophage uptake of NPs after 2 h and 24 h exposures in serum-free media or after a 24 h exposure in serum-free media containing cholesterol (20 μg/mL). All images were taken at 100x magnification. Arrows indicate macrophage internalized NPs.