Review Article

Nanosuspension Technologies for Delivery of Poorly Soluble Drugs

Table 2

Examples of marketed nanosuspensions produced by media milling technique.

Trade nameDrugIndicationDosage formCompanyStatus

RapamuneSirolimusImmunosuppressiveOral suspension/tablet
1-2 mg
WyethMarketed in 2000
TricorFenofibrateHypercholesterolemiaOral tablet
48–145 mg
AbbottMarketed in 2004
EmendAprepitantAntiemeticsOral capsule
80–125 mg
MerckMarketed in 2003
Megace ESMegestrolAntianorexia, cachexiaOral suspension
125 mg/mL
Par PharmaceuticalsMarketed in 2005