Development of a Composite Electrospun Polyethylene Terephthalate-Polyglycolic Acid Material: Potential Use as a Drug-Eluting Vascular Graft

Figure 3

Spatial fiber distribution in coelectrospun ePET/ePGA-d polymer using DyLight labeling and adjustable fiber ratio within the graft material: confocal microscopy images of fluorescently labeled coelectrospun ePET/ePGA-d polymer reveal sharp fiber and compound separation (a). Blue fluorescent filter highlights ePET fibers within the coelectrospun ePET/ePGA-d polymer. Red fluorescent filter highlights DyLight 549 containing ePGA fibers within the ePET/ePGA-d material. Representative images of three separate areas within the length of coelectrospun material with varying fiber ratio (b). (Top row) Only DyLight 549 containing ePGA fibers are present. (Middle row) A few blue ePET fibers are intertwined with the ePGA fibers. (Bottom row) A roughly equal fiber frequency of ePET and ePGA is present.

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