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Magnetic core-size (diameter) | Polymer/analyte | LCST | Affinity ligand/application | Reference/note |
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Fe3O4 polystyrene- (Therma-Max) 100 nm | PINAAm/thyroid stimulating hormone (TSH) | 22°C | β-antibody/TSH isolation and detection (Immunoassay) | [46] |
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Fe3O4-SiO2-80 nm | Poly(2-(2-methoxyethoxy)ethyl methacrylate-co-methacrylic acid-co-N-(4-vinyl)-benzyl iminodiacetic acid) P(MEO2MA-co-MAA-co-VBIDA)/Lysosome | 15–25°C | Molecularly imprinted lysosome receptor/thermal capture and release of lysosome | [47] |
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γ-Fe2O3-SiO2-5 μm | Poly(N-vinylcaprolactam) (PNVCL)/Bovine Serum Albumin (BSA) | 33.4°C | Hydrophobic interaction/protein separation-purification | [48]/size measurement was based on SEM of whole assembly |
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Fe3O4-100 nm | Poly(polyethylene glycol-co-N-isopropylacrylamide) poly(PEG-co-PINAAm)/lysozyme | 40°C | Hydrophobic interaction/protein separation-purification | [49]/size measurement based on TEM of aggregates due to inclusion complexes between cyclodextrin and PEG |
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PLGA-iron oxide MNPs- (Meliorum technologies, Rochester, NY) silica microparticles-50–100 μm | Poly(N-isopropylacrylamide-co-allylamine) poly(NIPAAm-co-AH)/stem cells | 33°C | CD34 antibodies/isolation, enrichment, and detachment of endothelial progenitor cells (EPCs) | [50]/size measurement was based on SEM of whole assembly |
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Fe3O4-100 nm | Poly(N,N′-isopropylacrylamide-co-N-methacroyl-N′-biotinylpropylenediamine) (P(NIPAAm-co-MBPDA))/ZZ-displaying yeast cells | 30°C | Anti-goat IgG (heavy and light chains) (rabbit IgG)/affinity selection and separation of target cells from model yeast cells | [51]/size measurement was based on DLS of whole assembly |
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Fe3O4–dextran- (Therma-Max) 70 nm | Poly(N-acryloyl glycinamide-co-N-(3-biotinamidepropyl)-methacrylamide) P(NAGAM-co-NBPMA) | 18°C (UCST) | (i) CD4 antibody/capture and enrichment of Arabidopsis protoplasts (plant cells) (ii) Silkworm storage protein (SP2)/anti-SP2 antibody | [52]/size measurement was based on DLS of whole assembly |
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