Research Article

Development of Drug Loaded Nanoparticles Binding to Hydroxyapatite Based on a Bisphosphonate Modified Nonionic Surfactant

Figure 10

The effects of free calcium ion on the HA binding to Pa-NPs. (a) The effects of free calcium on the integrity of prepared complex of HA/Pa-NPs. (b) The effects of free calcium on the in vitro binding of Pa-NP to HA.
(a)
(b)