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Journal of Nanomaterials
Volume 2015, Article ID 418932, 8 pages
http://dx.doi.org/10.1155/2015/418932
Research Article

Experimental Investigation of the Properties of Electrospun Nanofibers for Potential Medical Application

1Department of Epidemiology, School of Public Health, The Fourth Military Medical University, No. 169, Changle West Road, Xi’an, Shaanxi 710032, China
2School of Mechanical Engineering, Xi’an University of Science and Technology, No. 58, Yanta Road, Xi’an, Shaanxi 710054, China
3Clinics of Stomatology, Naval Logistics Branch of Hangzhou Sanatorium, Nanjing Military Area Command, Yuhuangshang Road, No. 76, Hangzhou, China
4College of Engineering, Design and Physical Sciences, Brunel University, Uxbridge, UK

Received 31 October 2014; Revised 8 January 2015; Accepted 23 January 2015

Academic Editor: Davood D. Ganji

Copyright © 2015 Anhui Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Polymer based nanofibers using ethylene-co-vinyl alcohol (EVOH) were fabricated by electrospinning technology. The nanofibers were studied for potential use as dressing materials for skin wounds treatment. Properties closely related to the clinical requirements for wound dressing were investigated, including the fluid uptake ability (FUA), the water vapour transmission rate (WVTR), the bacteria control ability of nanofibers encapsulated with different antibacterial drugs, and Ag of various concentrations. Nanofibre degradation under different environmental conditions was also studied for the prospect of long term usage. The finding confirms the potential of EVOH nanofibers for wound dressing application, including the superior performance compared to cotton gauze and the strong germ killing capacity when Ag particles are present in the nanofibers.