Interaction between Iron Oxide Nanoparticles and HepaRG Cells: A Preliminary In Vitro Evaluation

Figure 8

Typical chromatogram obtained with 250 μM diclofenac (a) and 20 μM sunitinib (b) metabolization tests during 5 hours or 6 hours, respectively. Unlabeled cells are represented in black color and labeled cells (17-hour incubation time with nanoparticles ([Fe] = 2 mM)) in blue color. Unlabeled cells gave higher metabolites areas than labeled cells.

(a)

(b)