Recent Advances in FePt Nanoparticles for Biomedicine

Figure 2

Biomedical applications of functionalized FePt MNPs: (a) a CT image of the MBT2 tumor-bearing mice 24 h after being injected with anti-Her2 antibody-FePt nanoparticles [21]; (b) T₂-weighted MRI of KB tumor-bearing nude mice 24 h after being injected with FePt@Fe₂O₃-PEG-FA nanoparticles [47]; (c) fluorescence image of C4-2 PSMA-positive after 10 min of incubation with J591-DSPE-SIPPs [59]; (d) extensive hematoma around the tumors on PTX alone injected mice (A), no such side effect on mice injected with J591-SPMs (B) [1]; (e) the principle of magnetic heat induction [2]; (f) photothermolysis images of the EMT-6 cancer cell induced by FePt nanoparticles under w10 mJ/cm² [44].