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Journal of Nanomaterials
Volume 2015, Article ID 537598, 8 pages
http://dx.doi.org/10.1155/2015/537598
Research Article

Evaluation of Biosourced Alkyd Nanoemulsions as Drug Carriers

1School of Postgraduate Studies and Research, International Medical University, No. 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000 Kuala Lumpur, Malaysia
2School of Pharmacy, International Medical University, No. 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000 Kuala Lumpur, Malaysia
3Department of Chemistry, Faculty of Science, University of Malaya, Lembah Pantai, 50603 Kuala Lumpur, Malaysia
4ULTI Pharmaceuticals, 19 Pembroke Street, Hamilton Lake, Hamilton 3204, New Zealand

Received 27 August 2015; Accepted 15 October 2015

Academic Editor: Michele Laus

Copyright © 2015 Siew Yong Teo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Karak, Vegetable Oil-Based Polymers: Properties, Processing and Applications, Elsevier, New York, NY, USA, 2012.
  2. A. I. Aigbodion and F. E. Okieimen, “An investigation of the utilisation of African locust bean seed oil in the preparation of alkyd resins,” Industrial Crops and Products, vol. 13, no. 1, pp. 29–34, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. A. I. Aigbodion and C. K. S. Pillai, “Synthesis and molecular weight characterization of rubber seed oil-modified alkyd resins,” Journal of Applied Polymer Science, vol. 79, no. 13, pp. 2431–2438, 2001. View at Google Scholar · View at Scopus
  4. S.-N. Gan and B.-Y. Tan, “FTIR studies of the curing reactions of palm oil alkyd-melamine enamels,” Journal of Applied Polymer Science, vol. 80, no. 12, pp. 2309–2315, 2001. View at Publisher · View at Google Scholar · View at Scopus
  5. S. N. Gan and D. T. C. Ang, “Development of palm oil-based alkyds as UV curable coatings,” Pigment & Resin Technology, vol. 41, no. 5, pp. 302–310, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Ataei, R. Yahya, and S. N. Gan, “Palm oleic acid based alkyds: effect of the fatty acid content on the polyesterification kinetics,” Journal of Polymers and the Environment, vol. 19, no. 2, pp. 540–545, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Y. Lee and S. N. Gan, “The adhesion properties of natural rubber pressure-sensitive adhesives using palm kernel oil-based alkyd resins as a tackifier,” Composite Interfaces, vol. 20, no. 3, pp. 177–188, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. E. E. Ilodigwe, L. U. Ndunagu, D. L. Ajaghaku, and U. A. Utoh-Nedosa, “Evaluation of the wound healing activity of a polyherbal remedy,” Annals of Biological Research, vol. 3, no. 11, pp. 5393–5398, 2012. View at Google Scholar
  9. S. Sasidharan, R. Nilawatyi, R. Xavier, L. Y. Latha, and R. Amala, “Wound healing potential of Elaeis guineensis Jacq leaves in an infected albino rat model,” Molecules, vol. 15, no. 5, pp. 3186–3199, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. O. C. Ugbogu, R. A. Onyeagba, and O. A. Chigbu, “Lauric acid content and inhibitory effect of palm kernel oil on two bacterial isolates and Candida albicans,” African Journal of Biotechnology, vol. 5, no. 11, pp. 1045–1047, 2006. View at Google Scholar · View at Scopus
  11. V. Borhade, S. Pathak, S. Sharma, and V. Patravale, “Clotrimazole nanoemulsion for malaria chemotherapy. Part I. Preformulation studies, formulation design and physicochemical evaluation,” International Journal of Pharmaceutics, vol. 431, no. 1-2, pp. 138–148, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. K. Jain, R. Suresh Kumar, S. Sood, and K. Gowthamarajan, “Enhanced oral bioavailability of atorvastatin via oil-in-water nanoemulsion using aqueous titration method,” Journal of Pharmaceutical Sciences and Research, vol. 5, no. 1, pp. 18–25, 2013. View at Google Scholar · View at Scopus
  13. M. S. Alam, M. S. Ali, N. Alam, M. R. Siddiqui, M. Shamim, and M. Safhi, “In vivo study of clobetasol propionate loaded nanoemulsion for topical application in psoriasis and atopic dermatitis,” Drug Invention Today, vol. 5, no. 1, pp. 8–12, 2013. View at Publisher · View at Google Scholar
  14. A. Garud, D. Singh, and N. Garud, “Solid lipid nanoparticles (SLN): method, characterization and applications,” International Current Pharmaceutical Journal, vol. 1, no. 11, pp. 384–393, 2012. View at Publisher · View at Google Scholar
  15. D. S. Bernardi, T. A. Pereira, N. R. Maciel et al., “Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments,” Journal of Nanobiotechnology, vol. 9, no. 44, pp. 1–9, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. H. Sun, K. Liu, W. Liu et al., “Development and characterization of a novel nanoemulsion drug-delivery system for potential application in oral delivery of protein drugs,” International Journal of Nanomedicine, vol. 7, pp. 5529–5543, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. Y. Zhang, J. Gao, H. Zheng, R. Zhang, and Y. Han, “The preparation of 3,5-dihydroxy-4-isopropylstilbene nanoemulsion and in vitro release,” International Journal of Nanomedicine, vol. 6, pp. 649–657, 2011. View at Google Scholar · View at Scopus
  18. G. Z. Abdullah, M. F. Abdulkarim, I. M. Salman et al., “Stability studies of nano-scaled emulsions containing ibuprofen for topical delivery,” International Journal of Drug Delivery, vol. 3, no. 1, pp. 74–82, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. J. S. Lim, S. F. Wong, M. C. Law, Y. Samyudia, and S. S. B. Dol, “A review on the effects of emulsions on flow behaviours and common factors affecting the stability of emulsions,” Journal of Applied Sciences, vol. 15, no. 2, pp. 167–172, 2015. View at Publisher · View at Google Scholar · View at Scopus
  20. C. V. Nikiforidis, O. A. Karkani, and V. Kiosseoglou, “Exploitation of maize germ for the preparation of a stable oil-body nanoemulsion using a combined aqueous extraction-ultrafiltration method,” Food Hydrocolloids, vol. 25, no. 5, pp. 1122–1127, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. J. M. de Morais, O. D. H. dos Santos, T. Delicato, and P. A. da Rocha-Filho, “Characterization and evaluation of electrolyte influence on canola oil/water nano-emulsion,” Journal of Dispersion Science and Technology, vol. 27, no. 7, pp. 1009–1014, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Y. Teo, M. J. Rathbone, A. G. A. Coombes, S. Y. Lee, and S. N. Gan, “Development and validation of a stability-indicating isocratic reverse phase-liquid chromatography assay for determination of phenytoin in bulk and pharmaceutical formulations,” International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no. 8, pp. 258–263, 2015. View at Google Scholar
  23. E. S. Mahdi, A. M. Noor, M. H. Sakeena, G. Z. Abdullah, M. F. Abdulkarim, and M. A. Sattar, “Formulation and in vitro release evaluation of newly synthesized palm kernel oil esters-based nanoemulsion delivery system for 30% ethanolic dried extract derived from local Phyllanthus urinaria for skin antiaging,” International journal of nanomedicine, vol. 6, pp. 2499–2512, 2011. View at Google Scholar · View at Scopus
  24. M. J. Lucero, J. Vigo, and M. J. León, “A study of shear and compression deformations on hydrophilic gels of tretinoin,” International Journal of Pharmaceutics, vol. 106, no. 2, pp. 125–133, 1994. View at Publisher · View at Google Scholar · View at Scopus
  25. K. G. Marinova, R. G. Alargova, N. D. Denkov et al., “Charging of oil-water interfaces due to spontaneous adsorption of hydroxyl ions,” Langmuir, vol. 12, no. 8, pp. 2045–2051, 1996. View at Publisher · View at Google Scholar · View at Scopus
  26. A. C. Puhl, M. Fagundes, K. C. dos Santos et al., “Preparation and characterization of polymeric nanoparticles loaded with the flavonoid luteolin, by using factorial design,” International Journal of Drug Delivery, vol. 3, no. 4, pp. 683–698, 2011. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Jaworska, E. Sikora, and J. Ogonowski, “The influence of glicerides oil phase on O/W nanoemulsion formation by pic method,” Periodica Polytechnica: Chemical Engineering, vol. 58, pp. 43–48, 2014. View at Publisher · View at Google Scholar · View at Scopus
  28. N. Anarjan and C. P. Tan, “Effects of selected polysorbate and sucrose ester emulsifiers on the physicochemical properties of astaxanthin nanodispersions,” Molecules, vol. 18, no. 1, pp. 768–777, 2013. View at Publisher · View at Google Scholar · View at Scopus