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Journal of Nanomaterials
Volume 2015, Article ID 608432, 8 pages
http://dx.doi.org/10.1155/2015/608432
Research Article

Multifunctional Silica Nanoparticles Modified via Silylated-Decaborate Precursors

1Institut Charles Gerhardt, UMR 5253, CC 1701, Equipe Chimie Moléculaire et Organisation du Solide, Université de Montpellier, Place Eugéne Bataillon, 34090 Montpellier Cedex 05, France
2Laboratoire de Chimie de Coordination Inorganique et Organométallique LCIO, Université Libanaise, Faculté des Sciences I, Hadath, Lebanon
3Ecole Doctorale des Sciences et Technologie EDST, PRASE, Université Libanaise, Hadath, Lebanon

Received 15 August 2015; Accepted 8 October 2015

Academic Editor: Yuebing Zheng

Copyright © 2015 Fatima Abi-Ghaida et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A new class of multifunctional silica nanoparticles carrying boron clusters (10-vertex closo-decaborate) and incorporating luminescent centers (fluorescein) has been developed as potential probes/carriers for potential application in boron neutron capture therapy (BNCT). These silica nanoparticles were charged in situ with silylated-fluorescein fluorophores via the Stöber method and their surface was further functionalized with decaborate-triethoxysilane precursors. The resulting decaborate dye-doped silica nanoparticles were characterized by TEM, solid state NMR, DLS, nitrogen sorption, elemental analysis, and fluorescence spectroscopy.