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Journal of Nanomaterials
Volume 2015, Article ID 628405, 6 pages
Research Article

Enhanced Nanohydroxyapatite Formation Using a Hydrolyzed Gelatin

1State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, China
2Department of Ultrasound, Nanlou Clinic Division, Chinese People’s Liberation Army General Hospital, Beijing 100853, China

Received 2 August 2015; Revised 12 October 2015; Accepted 28 October 2015

Academic Editor: Andrea Falqui

Copyright © 2015 Ding Ding et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Hydroxyapatite (HAP) nanoparticles were synthesized at room temperature using hydrolyzed gelatin (HG) as an additive. The crystallinity of HAP particles can be effectively controlled by adjusting the concentration of HG additive and the pH value of reaction system. The synthesized product was analyzed by Fourier transform infrared (FTIR) spectrometer, energy dispersive spectrometer (EDS), X-ray diffractometry (XRD), and transmission electron microscope (TEM). Meanwhile, it was proved that, with HG additive, HAP can be prepared with the calcium-phosphorus ratio of not only 1.67 but also 1.50. Conventionally, HAP particles need to be synthesized at high temperature with iCa/P = 1.67. Therefore, we believe that this study provides a novel strategy for the preparation of nano-HAP.