Journal of Nanomaterials / 2015 / Article / Tab 3

Research Article

Optimization and Characterization of Artesunate-Loaded Chitosan-Decorated Poly(D,L-lactide-co-glycolide) Acid Nanoparticles

Table 3

The optimal formulation of ART/PLGA-CS NPs.

Optimized independent variablesPredicted responsesObserved responses
CS/PLGA ratiopH of CS solutionTemp. (°C)Size (nm)Zeta potential (mV)Size (nm)Bias (%)Zeta potential (mV)Bias (%)

0.403.221.5188.935.0193.1 ± 1.0122.2236.2 ± 1.043.43

Bias (%) = ((observed response − predicted response)/predicted response) × 100.

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