Preparation and Evaluation of Pralidoxime-Loaded PLGA Nanoparticles as Potential Carriers of the Drug across the Blood Brain Barrier

Table 2

Mean particle size, polydispersity index (PDI), and zeta potential for pralidoxime-loaded PLGA nanoparticles with different drug : polymer ratio.

Drug/polymer ratio	Particle size (nm)	Zeta potential (mV)	PDI
1 : 1	386.6 ± 15.33	5.04 ± 0.35	0.323 ± 0.021
1 : 2	304.7 ± 7.167	3.31 ± 0.27	0.180 ± 0.032
1 : 4	322.8 ± 2.193	5.98 ± 0.30	0.203 ± 0.001

Data represented as mean ± SD.