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Journal of Nanomaterials
Volume 2015 (2015), Article ID 712359, 9 pages
Research Article

Synthesis of Monodispersed Gold Nanoparticles with Exceptional Colloidal Stability with Grafted Polyethylene Glycol-g-polyvinyl Alcohol

1Department of Pharmaceutics & Pharmaceutical Technology, Faculty of Pharmacy, The University of Jordan, Amman 11942, Jordan
2Department of Chemistry, Faculty of Science, The University of Jordan, Amman 11942, Jordan

Received 23 December 2014; Accepted 3 February 2015

Academic Editor: Subrata Kundu

Copyright © 2015 Alaaldin M. Alkilany et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Herein, we report the synthesis of spherical gold nanoparticles with tunable core size (23–79 nm) in the presence of polyethylene glycol-g-polyvinyl alcohol (PEG-g-PVA) grafted copolymer as a reducing, capping, and stabilizing agent in a one-step protocol. The resulted PEG-g-PVA-capped gold nanoparticles are monodispersed with an exceptional colloidal stability against salt addition, repeated centrifugation, and extensive dialysis. The effect of various synthesis parameters and the kinetic/mechanism of the nanoparticle formation are discussed.