Gold Nanoparticles Increase PLK1-Specific Small Interfering RNA Transfection and Induce Apoptosis of Drug Resistance Breast Cancer Cells

Figure 4

Internalization of Lipofectamine 2000-siRNA (Lip-siRNA) and GNPs-siRNA (the weight ratio was 1) by MCF-7/MDR1 cells after 4 h and 24 h incubation. DAPI (blue) stains cell nuclei and Cy 5 (red) indicates siRNA. Scale bars: 20 μm.