Efficient Synthesis of Single-Chain Polymer Nanoparticles via Amide Formation

Figure 3

SEC/SLS traces showing the progressive reduction in hydrodynamic size of P(MMA-co-AEMA) copolymer P1 upon intrachain cross-linking via amide formation. Reaction time: 0 h (dotted curve), 12 h (dashed curve), and 24 h (continuous curve).