Efficient Synthesis of Single-Chain Polymer Nanoparticles via Amide Formation

Table 1

Characteristics of precursors and SCNPs synthesized in this work by RAFT polymerization.

Code	Yield (%)			Ð =	AEMA	Size
		(kDa)^a	(kDa)^a		(mol%)^b	(nm)^c
P1	46	39.1	40.9	1.05	30	9.5
P2	70	182.0	248.1	1.35	27	22.8
N1	79	39.0	41.0	1.05	30	6.4
N2	75	213.6	267.0	1.25	27	12.5

As determined by SEC/SLS. ^bAs determined by ¹H NMR spectroscopy. ^cAs determined by DLS.