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Journal of Nanomaterials
Volume 2015, Article ID 787862, 13 pages
http://dx.doi.org/10.1155/2015/787862
Review Article

Preparation and Application of Fluorescent Carbon Dots

Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China Institute of Technology, Nanchang 330013, China

Received 20 May 2015; Accepted 21 June 2015

Academic Editor: Xiaogang Han

Copyright © 2015 Jun Zuo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. U. Resch-Genger, M. Grabolle, S. Cavaliere-Jaricot, R. Nitschke, and T. Nann, “Quantum dots versus organic dyes as fluorescent labels,” Nature Methods, vol. 5, no. 9, pp. 763–775, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. A. R. Clapp, T. Pons, I. L. Medintz et al., “Two-photon excitation of quantum-dot-based fluorescence resonance energy transfer and its applications,” Advanced Materials, vol. 19, no. 15, pp. 1921–1926, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. C. E. Probst, P. Zrazhevskiy, V. Bagalkot, and X. Gao, “Quantum dots as a platform for nanoparticle drug delivery vehicle design,” Advanced Drug Delivery Reviews, vol. 65, no. 5, pp. 703–718, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. H. J. Li, X. Wei, Y. Q. Xu et al., “Determination of aspirin using functionalized cadmium-tellurium quantum dots as a fluorescence probe,” Analytical Letters, vol. 48, no. 7, pp. 1117–1127, 2015. View at Publisher · View at Google Scholar
  5. D. R. Larson, W. R. Zipfel, R. M. Williams et al., “Water-soluble quantum dots for multiphoton fluorescence imaging in vivo,” Science, vol. 300, no. 5624, pp. 1434–1436, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. R. Liu, D. Wu, S. Liu, K. Koynov, W. Knoll, and Q. Li, “An aqueous route to multicolor photoluminescent carbon dots using silica spheres as carriers,” Angewandte Chemie, vol. 48, no. 25, pp. 4598–4601, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. J. Geys, A. Nemmar, E. Verbeken et al., “Acute toxicity and prothrombotic effects of quantum dots: impact of surface charge,” Environmental Health Perspectives, vol. 116, no. 12, pp. 1607–1613, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. X. Xu, R. Ray, Y. Gu et al., “Electrophoretic analysis and purification of fluorescent single-walled carbon nanotube fragments,” Journal of the American Chemical Society, vol. 126, no. 40, pp. 12736–12737, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. L. Cao, X. Wang, M. J. Meziani et al., “Carbon dots for multiphoton bioimaging,” Journal of the American Chemical Society, vol. 129, no. 37, pp. 11318–11319, 2007. View at Publisher · View at Google Scholar · View at Scopus
  10. H. Zhang, Y. Chen, M. Liang et al., “Solid-phase synthesis of highly fluorescent nitrogen-doped carbon dots for sensitive and selective probing ferric ions in living cells,” Analytical Chemistry, vol. 86, no. 19, pp. 9846–9852, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Y. Park, H. U. Lee, E. S. Park et al., “Photoluminescent green carbon nanodots from food-waste-derived sources: large-scale synthesis, properties, and biomedical applications,” ACS Applied Materials & Interfaces, vol. 6, no. 5, pp. 3365–3370, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. S.-L. Hu, K.-Y. Niu, J. Sun, J. Yang, N.-Q. Zhao, and X.-W. Du, “One-step synthesis of fluorescent carbon nanoparticles by laser irradiation,” Journal of Materials Chemistry, vol. 19, no. 4, pp. 484–488, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. H. Peng and J. Travas-Sejdic, “Simple aqueous solution route to luminescent carbogenic dots from carbohydrates,” Chemistry of Materials, vol. 21, no. 23, pp. 5563–5565, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Liu, T. Ye, and C. Mao, “Fluorescent carbon nanoparticles derived from candle soot,” Angewandte Chemie International Edition, vol. 46, no. 34, pp. 6473–6475, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. X. Jia, J. Li, and E. Wang, “One-pot green synthesis of optically pH-sensitive carbon dots with upconversion luminescence,” Nanoscale, vol. 4, no. 18, pp. 5572–5575, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. L. Wang, S.-J. Zhu, H.-Y. Wang et al., “Common origin of green luminescence in carbon nanodots and graphene quantum dots,” ACS Nano, vol. 8, no. 3, pp. 2541–2547, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. K. Wang, Z. Gao, G. Gao et al., “Systematic safety evaluation on photoluminescent carbon dots,” Nanoscale Research Letters, vol. 8, no. 1, pp. 1–9, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. H. Li, Z. Kang, Y. Liu, and S.-T. Lee, “Carbon nanodots: synthesis, properties and applications,” Journal of Materials Chemistry, vol. 22, no. 46, pp. 24230–24253, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. H. Jiang, F. Chen, M. G. Lagally, and F. S. Denes, “New strategy for synthesis and functionalization of carbon nanoparticles,” Langmuir, vol. 26, no. 3, pp. 1991–1995, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. L. Zheng, Y. Chi, Y. Dong, J. Lin, and B. Wang, “Electrochemiluminescence of water-soluble carbon nanocrystals released electrochemically from graphite,” Journal of the American Chemical Society, vol. 131, no. 13, pp. 4564–4565, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Lu, J.-X. Yang, J. Wang, A. Lim, S. Wang, and K. P. Loh, “One-pot synthesis of fluorescent carbon nanoribbons, nanoparticles, and graphene by the exfoliation of graphite in ionic liquids,” ACS Nano, vol. 3, no. 8, pp. 2367–2375, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. J. Zhou, C. Booker, R. Li et al., “An electrochemical avenue to blue luminescent nanocrystals from multiwalled carbon nanotubes (MWCNTs),” Journal of the American Chemical Society, vol. 129, no. 4, pp. 744–745, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. Q.-L. Zhao, Z.-L. Zhang, B.-H. Huang, J. Peng, M. Zhang, and D.-W. Pang, “Facile preparation of low cytotoxicity fluorescent carbon nanocrystals by electrooxidation of graphite,” Chemical Communications, no. 41, pp. 5116–5118, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. S.-T. Yang, L. Cao, P. G. Luo et al., “Carbon dots for optical imaging in vivo,” Journal of the American Chemical Society, vol. 131, no. 32, pp. 11308–11309, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. H. M. R. Gonçalves, A. J. Duarte, and J. C. G. Esteves da Silva, “Optical fiber sensor for Hg(II) based on carbon dots,” Biosensors & Bioelectronics, vol. 26, no. 4, pp. 1302–1306, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. Y.-P. Sun, B. Zhou, Y. Lin et al., “Quantum-sized carbon dots for bright and colorful photoluminescence,” Journal of the American Chemical Society, vol. 128, no. 24, pp. 7756–7757, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. S. Hu, J. Liu, J. Yang, Y. Wang, and S. Cao, “Laser synthesis and size tailor of carbon quantum dots,” Journal of Nanoparticle Research, vol. 13, no. 12, pp. 7247–7252, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. C.-I. Wang, A. P. Periasamy, and H.-T. Chang, “Photoluminescent C-dots@RGO probe for sensitive and selective detection of acetylcholine,” Analytical Chemistry, vol. 85, no. 6, pp. 3263–3270, 2013. View at Publisher · View at Google Scholar · View at Scopus
  29. Z. Qian, X. Shan, L. Chai, J. Ma, J. Chen, and H. Feng, “Si-doped carbon quantum dots: a facile and general preparation strategy, bioimaging application, and multifunctional sensor,” ACS Applied Materials & Interfaces, vol. 6, no. 9, pp. 6797–6805, 2014. View at Publisher · View at Google Scholar · View at Scopus
  30. Y. Xu, X.-H. Jia, X.-B. Yin, X.-W. He, and Y.-K. Zhang, “Carbon quantum dot stabilized gadolinium nanoprobe prepared via a one-pot hydrothermal approach for magnetic resonance and fluorescence dual-modality bioimaging,” Analytical Chemistry, vol. 86, no. 24, pp. 12122–12129, 2014. View at Publisher · View at Google Scholar · View at Scopus
  31. H. Dong, A. Kuzmanoski, D. M. Gößl, R. Popescu, D. Gerthsen, and C. Feldmann, “Polyol-mediated C-dot formation showing efficient Tb3+/Eu3+ emission,” Chemical Communications, vol. 50, no. 56, pp. 7503–7506, 2014. View at Publisher · View at Google Scholar
  32. M. X. Gao, C. F. Liu, Z. L. Wu et al., “A surfactant-assisted redox hydrothermal route to prepare highly photoluminescent carbon quantum dots with aggregation-induced emission enhancement properties,” Chemical Communications, vol. 49, no. 73, pp. 8015–8017, 2013. View at Publisher · View at Google Scholar · View at Scopus
  33. S. C. Ray, A. Saha, N. R. Jana, and R. Sarkar, “Fluorescent carbon nanoparticles: synthesis, characterization, and bioimaging application,” Journal of Physical Chemistry C, vol. 113, no. 43, pp. 18546–18551, 2009. View at Publisher · View at Google Scholar · View at Scopus
  34. Y. Tang, Y. Su, N. Yang, L. Zhang, and Y. Lv, “Carbon nitride quantum dots: a novel chemiluminescence system for selective detection of free chlorine in water,” Analytical Chemistry, vol. 86, no. 9, pp. 4528–4535, 2014. View at Publisher · View at Google Scholar · View at Scopus
  35. H. Zhu, X. Wang, Y. Li, Z. Wang, F. Yang, and X. Yang, “Microwave synthesis of fluorescent carbon nanoparticles with electrochemiluminescence properties,” Chemical Communications, no. 34, pp. 5118–5120, 2009. View at Publisher · View at Google Scholar · View at Scopus
  36. Q. Wang, X. Liu, L. Zhang, and Y. Lv, “Microwave-assisted synthesis of carbon nanodots through an eggshell membrane and their fluorescent application,” The Analyst, vol. 137, no. 22, pp. 5392–5397, 2012. View at Publisher · View at Google Scholar · View at Scopus
  37. S. Chandra, P. Das, S. Bag, D. Laha, and P. Pramanik, “Synthesis, functionalization and bioimaging applications of highly fluorescent carbon nanoparticles,” Nanoscale, vol. 3, no. 4, pp. 1533–1540, 2011. View at Publisher · View at Google Scholar · View at Scopus
  38. Y. Yang, J. Cui, M. Zheng et al., “One-step synthesis of amino-functionalized fluorescent carbon nanoparticles by hydrothermal carbonization of chitosan,” Chemical Communications, vol. 48, no. 3, pp. 380–382, 2012. View at Publisher · View at Google Scholar · View at Scopus
  39. G. Oza, K. Oza, S. Pandey et al., “A green route towards highly photoluminescent and cytocompatible carbon dot synthesis and its separation using sucrose density gradient centrifugation,” Journal of Fluorescence, vol. 25, no. 1, pp. 9–14, 2015. View at Publisher · View at Google Scholar · View at Scopus
  40. G. E. Lecroy, S. K. Sonkar, F. Yang et al., “Toward structurally defined carbon dots as ultracompact fluorescent probes,” ACS Nano, vol. 8, no. 5, pp. 4522–4529, 2014. View at Publisher · View at Google Scholar · View at Scopus
  41. A. B. Bourlinos, A. Stassinopoulos, D. Anglos, R. Zboril, M. Karakassides, and E. P. Giannelis, “Surface functionalized carbogenic quantum dots,” Small, vol. 4, no. 4, pp. 455–458, 2008. View at Publisher · View at Google Scholar · View at Scopus
  42. J. Zong, X. Yang, A. Trinchi et al., “Carbon dots as fluorescent probes for ‘off-on’ detection of Cu2+ and l-cysteine in aqueous solution,” Biosensors & Bioelectronics, vol. 51, pp. 330–335, 2014. View at Publisher · View at Google Scholar · View at Scopus
  43. L. Cao, S. Sahu, P. Anilkumar et al., “Carbon nanoparticles as visible-light photocatalysts for efficient CO2 conversion and beyond,” Journal of the American Chemical Society, vol. 133, no. 13, pp. 4754–4757, 2011. View at Publisher · View at Google Scholar · View at Scopus
  44. H. Zhang, H. Ming, S. Lian et al., “Fe2O3/carbon quantum dots complex photocatalysts and their enhanced photocatalytic activity under visible light,” Dalton Transactions, vol. 40, no. 41, pp. 10822–10825, 2011. View at Publisher · View at Google Scholar · View at Scopus
  45. X. Chen and S. S. Mao, “Titanium dioxide nanomaterials: synthesis, properties, modifications and applications,” Chemical Reviews, vol. 107, no. 7, pp. 2891–2959, 2007. View at Publisher · View at Google Scholar · View at Scopus
  46. X. Zhang, F. Wang, H. Huang et al., “Carbon quantum dot sensitized TiO2 nanotube arrays for photoelectrochemical hydrogen generation under visible light,” Nanoscale, vol. 5, no. 6, pp. 2274–2278, 2013. View at Publisher · View at Google Scholar · View at Scopus
  47. X. Zhang, H. Huang, J. Liu, Y. Liu, and Z. Kang, “Carbon quantum dots serving as spectral converters through broadband upconversion of near-infrared photons for photoelectrochemical hydrogen generation,” Journal of Materials Chemistry A, vol. 1, no. 38, pp. 11529–11533, 2013. View at Publisher · View at Google Scholar · View at Scopus
  48. X. Guo, C.-F. Wang, Z.-Y. Yu, L. Chen, and S. Chen, “Facile access to versatile fluorescent carbon dots toward light-emitting diodes,” Chemical Communications, vol. 48, no. 21, pp. 2692–2694, 2012. View at Publisher · View at Google Scholar · View at Scopus
  49. F. Wang, Y.-H. Chen, C.-Y. Liu, and D.-G. Ma, “White light-emitting devices based on carbon dots' electroluminescence,” Chemical Communications, vol. 47, no. 12, pp. 3502–3504, 2011. View at Publisher · View at Google Scholar · View at Scopus
  50. X. Zhang, H. Ming, R. Liu et al., “Highly sensitive humidity sensing properties of carbon quantum dots films,” Materials Research Bulletin, vol. 48, no. 2, pp. 790–794, 2013. View at Publisher · View at Google Scholar · View at Scopus
  51. Y. Fan, H. Cheng, C. Zhou et al., “Honeycomb architecture of carbon quantum dots: a new efficient substrate to support gold for stronger SERS,” Nanoscale, vol. 4, no. 5, pp. 1776–1781, 2012. View at Publisher · View at Google Scholar
  52. W. Lu, X. Qin, S. Liu et al., “Economical, green synthesis of fluorescent carbon nanoparticles and their use as probes for sensitive and selective detection of mercury(II) ions,” Analytical Chemistry, vol. 84, no. 12, pp. 5351–5357, 2012. View at Publisher · View at Google Scholar · View at Scopus
  53. R. H. Liu, H. T. Li, W. Q. Kong et al., “Ultra-sensitive and selective Hg2+ detection based on fluorescent carbon dots,” Materials Research Bulletin, vol. 48, no. 7, pp. 2529–2534, 2013. View at Publisher · View at Google Scholar · View at Scopus
  54. R. Zhang and W. Chen, “Nitrogen-doped carbon quantum dots: facile synthesis and application as a ‘turn-off’ fluorescent probe for detection of Hg2+ ions,” Biosensors & Bioelectronics, vol. 55, pp. 83–90, 2014. View at Publisher · View at Google Scholar · View at Scopus
  55. X. Cui, L. Zhu, J. Wu et al., “A fluorescent biosensor based on carbon dots-labeled oligodeoxyribonucleotide and graphene oxide for mercury (II) detection,” Biosensors & Bioelectronics, vol. 63, pp. 506–512, 2015. View at Publisher · View at Google Scholar · View at Scopus
  56. A. Salinas-Castillo, M. Ariza-Avidad, C. Pritz et al., “Carbon dots for copper detection with down and upconversion fluorescent properties as excitation sources,” Chemical Communications, vol. 49, no. 11, pp. 1103–1105, 2013. View at Publisher · View at Google Scholar · View at Scopus
  57. M. Vedamalai, A. P. Periasamy, C.-W. Wang et al., “Carbon nanodots prepared from o-phenylenediamine for sensing of Cu2+ ions in cells,” Nanoscale, vol. 6, no. 21, pp. 13119–13125, 2014. View at Publisher · View at Google Scholar · View at Scopus
  58. Y.-L. Zhang, L. Wang, H.-C. Zhang et al., “Graphitic carbon quantum dots as a fluorescent sensing platform for highly efficient detection of Fe3+ ions,” RSC Advances, vol. 3, no. 11, pp. 3733–3738, 2013. View at Publisher · View at Google Scholar · View at Scopus
  59. K. Qu, J. Wang, J. Ren, and X. Qu, “Carbon dots prepared by hydrothermal treatment of dopamine as an effective fluorescent sensing platform for the label-free detection of iron(III) ions and dopamine,” Chemistry A, vol. 19, no. 22, pp. 7243–7249, 2013. View at Publisher · View at Google Scholar · View at Scopus
  60. S. S. Wee, Y. H. Ng, and S. M. Ng, “Synthesis of fluorescent carbon dots via simple acid hydrolysis of bovine serum albumin and its potential as sensitive sensing probe for lead (II) ions,” Talanta, vol. 116, pp. 71–76, 2013. View at Publisher · View at Google Scholar · View at Scopus
  61. Z. Qian, J. Ma, X. Shan, H. Feng, L. Shao, and J. Chen, “Highly luminescent N-doped carbon quantum dots as an effective multifunctional fluorescence sensing platform,” Chemistry—A European Journal, vol. 20, no. 8, pp. 2254–2263, 2014. View at Publisher · View at Google Scholar · View at Scopus
  62. F. K. Du, F. Zeng, Y. H. Ming, and S. Wu, “Carbon dots-based fluorescent probes for sensitive and selective detection of iodide,” Microchimica Acta, vol. 180, no. 5-6, pp. 453–460, 2013. View at Publisher · View at Google Scholar · View at Scopus
  63. W. Bai, H. Zheng, Y. Long, X. Mao, M. Gao, and L. Zhang, “A carbon dots-based fluorescence turn-on method for DNA determination,” Analytical Sciences, vol. 27, no. 3, pp. 243–246, 2011. View at Publisher · View at Google Scholar · View at Scopus
  64. B. Xu, C. Zhao, W. Wei et al., “Aptamer carbon nanodot sandwich used for fluorescent detection of protein,” The Analyst, vol. 137, no. 23, pp. 5483–5486, 2012. View at Publisher · View at Google Scholar · View at Scopus
  65. V. N. Mehta, S. Jha, and S. K. Kailasa, “One-pot green synthesis of carbon dots by using Saccharum officinarum juice for fluorescent imaging of bacteria (Escherichia coli) and yeast (Saccharomyces cerevisiae) cells,” Materials Science & Engineering C, vol. 38, no. 1, pp. 20–27, 2014. View at Publisher · View at Google Scholar · View at Scopus
  66. L. Wang, Y. Yin, A. Jain, and H. Susan Zhou, “Aqueous phase synthesis of highly luminescent, nitrogen-doped carbon dots and their application as bioimaging agents,” Langmuir, vol. 30, no. 47, pp. 14270–14275, 2014. View at Publisher · View at Google Scholar · View at Scopus
  67. Y.-Y. Zhang, M. Wu, Y.-Q. Wang, X.-W. He, W.-Y. Li, and X.-Z. Feng, “A new hydrothermal refluxing route to strong fluorescent carbon dots and its application as fluorescent imaging agent,” Talanta, vol. 117, pp. 196–202, 2013. View at Publisher · View at Google Scholar · View at Scopus
  68. E. J. Goh, K. S. Kim, Y. R. Kim et al., “Bioimaging of hyaluronic acid derivatives using nanosized carbon dots,” Biomacromolecules, vol. 13, no. 8, pp. 2554–2561, 2012. View at Publisher · View at Google Scholar · View at Scopus
  69. C.-W. Lai, Y.-H. Hsiao, Y.-K. Peng, and P.-T. Chou, “Facile synthesis of highly emissive carbon dots from pyrolysis of glycerol; gram scale production of carbon dots/mSiO2 for cell imaging and drug release,” Journal of Materials Chemistry, vol. 22, no. 29, pp. 14403–14409, 2012. View at Publisher · View at Google Scholar · View at Scopus
  70. M. Zheng, S. Liu, J. Li et al., “Integrating oxaliplatin with highly luminescent carbon dots: an unprecedented theranostic agent for personalized medicine,” Advanced Materials, vol. 26, no. 21, pp. 3554–3560, 2014. View at Publisher · View at Google Scholar · View at Scopus