Recent Trends in Preparation of Poly(lactide-co-glycolide) Nanoparticles by Mixing Polymeric Organic Solution with Antisolvent

Figure 3

SEM micrographs of PLGA nanoparticles prepared by (a) the microfluidic approach and (b) the conventional nanoprecipitation method using bulk solutions. The mean diameters of PLGA nanoparticles prepared by (a) and (b) methods are 148 ± 14 nm and 211 ± 70 nm, respectively (Xie and Smith, [130], publisher and licensee BioMed Central Ltd.).

(a)

(b)