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Journal of Nanomaterials
Volume 2015 (2015), Article ID 902836, 6 pages
http://dx.doi.org/10.1155/2015/902836
Research Article

Clinical Effects of Novel Nanoscaled Core Decompression Rods Combined with Umbilical Cord Mesenchymal Stem Cells on the Treatment of Early Osteonecrosis of the Femoral Head

1Department of Orthopedics, The First Hospital of Hebei Medical University, Shijiazhuang 050031, China
2Department of Cardiovasology III, The First Hospital of Hebei Medical University, Shijiazhuang 050031, China

Received 11 December 2014; Accepted 29 January 2015

Academic Editor: Shuming Zhang

Copyright © 2015 Hongyang Gao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Osteonecrosis of the femoral head (ONFH) is one of the most common diseases in orthopedics. In this study, we investigated the clinical effects of novel nanoscaled core decompression rods combined with mesenchymal stem cells on the treatment of the ONFH. 12 adult patients with early ONFH (at the stage of Ficat II) received the treatment using the implantation of novel nanoscaled core decompression rods combined with umbilical cord mesenchymal stem cells. The grade of the patients’ hip was scored by Harris marking system before and after the surgery, and then paired t-test was done. We assessed the curative efficiency based on the change of the patients before and after the surgery. In particular, the survival rate of femoral head was assessed at 12 months after the surgery. The results demonstrated that according to the standard of Harris Scoring, the average grade of hip joint before the surgery was points while average grade of hip joint at 12 months after the surgery was points. So, the implantation of the novel nanoscaled core decompression rods combined with mesenchymal stem cells had satisfactory clinical effects, suggesting that this implantation should be effective to treat early ONFH.