In Vitro and In Vivo Enhancement of Antitumoral Activity of Liposomal Antisense Oligonucleotides by Cineole as a Chemical Penetration Enhancer

Figure 5

RT-PCR determination of protein kinase C-α (PKC-α) expression. A549 cells were transfected with the liposomal antisense (As) or scrambled (Sc) oligodeoxynucleotides (ODN). Cells were incubated with either pure cell culture medium alone (left bars) or cineole-containing cell culture medium (right bars). Quantitative expressed target mRNA. GAPDH data are provided as control.