Effects of End-Terminal Capping on Transthyretin (105–115) Amyloid Protofibrils Using Steered Molecular Dynamics

Table 1

The tensile Young’s modulus of several amyloid fibrils for the comparison.

Structures	Elastic modulus (GPa)
hIAPP (SMD) [17, 18]	2.4–12
hIAPP (ENM) [19]	12–14
Aβ (SMD) [42–44]	12.4–17.2
TTR (experiment) [45]	2.6
TTR (our study)	6–8