Research Article

Molecular Mechanism of Enhanced Anticancer Effect of Nanoparticle Formulated LY2835219 via p16-CDK4/6-pRb Pathway in Colorectal Carcinoma Cell Line

Table 1

Characterization of LY2835219-loaded nanoparticles (mean ± SD, ).

FormulationLE (%)EE (%)Particle size (nm)Zeta potential (mV)

CNP/LY21.3 ± 5.241.7 ± 7.1195 ± 39.637.3 ± 1.5
HACNP/LY24.1 ± 3.536.9 ± 6.2217 ± 31.130.3 ± 2.2