Research Article

Preparation and Evaluation of Solid-Self-Emulsifying Drug Delivery System Containing Paclitaxel for Lymphatic Delivery

Table 5

Pharmacokinetic parameters of Ptx after the oral administration (20 mg/kg) of the Ptx reference and Ptx-loaded S-SEDDS in rats ( = 5).

ParametersOral administration
Ptx solutionS-SEDDS

(ng/mL)#84.6 ± 4.1259.5 ± 7.5
(hr) 1.8 ± 0.2 1.7 ± 0.2
(ng·hr/mL)#1816.5 ± 206.4 3308.5 ± 486.2

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