Research Article
In Vivo Investigation of ALBO-OS Scaffold Based on Hydroxyapatite and PLGA
Table 1
Numerical scale for evaluation of the skin reaction.
| | | Degree |
| | Erythema | | | Without erythema | 0 | | Mild erythema | 1 | | Well defined erythema | 2 | | Expressed erythema | 3 | | Heavy erythema (deep lesions, scabs, burns, and necrosis) | 4 | | Edema | | | Without edema | 0 | | Very mild edema | 1 | | Mild edema (well defined edges) | 2 | | Moderate edema (~1 mm thickness) | 3 | | Heavy edema (thickness > 1 mm, spreading out of application site) | 4 | | Total possible score of irritation | 8 |
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