Polymer Nanoparticle-Based Chemotherapy for Spinal Malignancies

Figure 2

(a) Typical of P(D,L-Leu)-b-PEG-b-P(D,L-Leu) (PDL) micelle. In vitro cytotoxicities of (A) DOX-loaded P(L-Leu)-b-PEG-b-P(L-Leu) (PL), (B) PDL micelles, and (C) free DOX against (b) MG63 and (c) SaOS-2 cells after incubation for 72 h. Data are presented as mean ± standard deviation (SD; ). (d) Release plots of DOX from DOX-loaded PL (A) and PDL micelles (B) in PBS. Data are presented as mean ± SD ().

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