Nanomechanical Characterization of Amyloid Fibrils Using Single-Molecule Experiments and Computational Simulations

Figure 10

(a) Length-dependent mechanical deformation mechanisms of amyloid fibrils. The upper panel shows the shear-like deformation of a short fibril, while the lower panel provides the bending deformation of a long fibril. (b) Length-dependent elastic stiffness of amyloid fibrils (black) and spider silk crystals (red). (c) Length-dependent rupture forces of amyloid fibrils (black) and spider silk crystals (red). Figures are adopted with permission from [23].

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