Penetration and Silencing Activity of VEGF Dicer Substrate siRNA Vectorized by Chitosan Nanoparticles in Monolayer Culture and a Solid Tumor Model In Vitro for Potential Application in Tumor Therapy

Figure 2

Encapsulation efficiency (a) of DsiRNA-CS nanoparticles prepared from different CS concentrations (0.1% to 0.4% w/v CS), . Binding efficiency (b) and heparin displacement assay (c) of DsiRNA-CS nanoparticles as determined by 4% w/v agarose gel electrophoresis.

(a)

(b)

(c)