Penetration and Silencing Activity of VEGF Dicer Substrate siRNA Vectorized by Chitosan Nanoparticles in Monolayer Culture and a Solid Tumor Model<i> In Vitro</i> for Potential Application in Tumor Therapy

<div>(a) Live/dead cell viability assay of DsiRNA-CS nanoparticles in DLD-1 cells after 24 h and 48 h incubation. Untreated cells (A, D), naked DsiRNA (B, E), and DsiRNA-CS nanoparticles (C, F) after 24 h and 48 h incubation, respectively (green and red colors represent viable and dead cells, resp.). (b) Internalization and localization of 6-FAM-labeled DsiRNA-CS nanoparticles in DLD-1 cells after 6 h incubation. Scale bar represents 10 <i>μ</i>m.</div>

Journal of Nanomaterials

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Figure 8: Penetration and Silencing Activity of VEGF Dicer Substrate siRNA Vectorized by Chitosan Nanoparticles in Monolayer Culture and a Solid Tumor Model<i> In Vitro</i> for Potential Application in Tumor Therapy 

Figure 8 | Penetration and Silencing Activity of VEGF Dicer Substrate siRNA Vectorized by Chitosan Nanoparticles in Monolayer Culture and a Solid Tumor Model In Vitro for Potential Application in Tumor Therapy 