Poly-γ-Glutamic Acid Nanoparticles Based Visible Light-Curable Hydrogel for Biomedical Application

Figure 1

Scheme of the chemical reaction for the modifications of γ-PGA. The first step is a crosslinking reaction, where the CDI activates the carboxyl groups and the EDA creates crosslinked γ-PGAs. 24 hours later, in the second step a methacrylation reaction takes place, where the remaining carboxyl groups will be activated by a new portion of CDI and the AEM will form methacrylated-PGA nanoparticles (MPGA-NPs).