Niosomes as Nanoparticular Drug Carriers: Fundamentals and Recent Applications

Table 2

Niosomes in targeted drug delivery.

Targeted tissue	Loaded therapeutic agent	Composition	Preparation method	Surface modification	Targeting molecule	References
Brain	Doxorubicin	Span 60, cholesterol, solulan C24, N-palmitoyl glucosamine	TLE-paddle method	—	N-Palmitoyl glucosamine	[30]
	Dynorphin-B	Span 60, cholesterol, solulan C24, N-palmitoyl glucosamine	Sonication	—	N-Palmitoyl glucosamine	[26]
	Vasoactive intestinal peptide	Span 60, cholesterol, solulan C24, N-palmitoyl glucosamine	Sonication	—	N-Palmitoyl glucosamine	[31]
Breast cancer	Doxorubicin	Oxidate pluronic L64, cholesterol	Thin-film hydration	EDC Chemistry	Transferrin	[24]
Chronic myelogenous leukemia	Doxorubicin	Tween 60, pluronic L64	Thin-film hydration	—	Magnetite	[32]
Epidermoid carcinoma	Hydroxycamptothecin	Span 60, cholesterol	Thin-film hydration	Periodate oxidation	Transferrin	[33]
	Doxorubicin	Span 60, cholesterol, solulan C24, N-palmitoyl glucosamine	Sonication	—	N-Palmitoyl glucosamine	[34]
Melanoma	Doxorubicin	Span 60, cholesterol, dicetyl phosphate, N-lauryl glucosamine	Ethanol injection method	—	N-Lauryl glucosamine	[35]