An Innovative Cell Microincubator for Drug Discovery Based on 3D Silicon Structures

Figure 3

Fluorescence microscopy images relative to HT1080 cells grown for 48 h on the flat regions of the silicon device. Cells are fixed and double stained with FITC and PI. Blue excitation for simultaneous emission of both fluorescent probes. Images (a) and (b) are at low magnification (20x); (c) and (d) are at higher magnification (40x). Images show the spindle cell morphology typical of the mesenchymal phenotype.

(a)

(b)

(c)

(d)