An Innovative Cell Microincubator for Drug Discovery Based on 3D Silicon Structures

Figure 9

Top view of the 3D-SMS populated by cells taken with the fluorescence microscope with green excitation for PI. The bright horizontal lines are the gaps (with cells inside) separating two silicon walls. The numbers (1–9) indicate the positions where we performed low coherence interferometric measurements to detect the cell inside the first gap (corresponding to positions 6-7); they are drawn outside the 3D-SMS region so that they do not mask any part of the 3D-SMS. The “upper section” of the fluorescence image is the region outside the 3D-SMS and does not contain significant details. The readout beam for interferometric testing arrives on the silicon device from that side.