Design and Characterization of Endostatin-Loaded Nanoparticles for In Vitro Antiangiogenesis in Squamous Cell Carcinoma

Figure 13

Cell viability/proliferation of treated and untreated oesophageal squamous cell carcinoma (KYSE-30) after 24-hour exposure to the nanoformulations at varying polymer concentrations. An unpaired -test, two-tailed values for native and endostatin-loaded nanoparticles when compared to the control untreated cells showed statistically significant differences at and , respectively. Meanwhile, there is no significant difference between native and endostatin-loaded nanoparticles for 125, 250, and 500 μg/mL after 24-hour treatment.