Preparation and Characterization of Folate-Targeted Fe₃O₄ Nanoparticle Codelivering Cisplatin and TFPI-2 Plasmid DNA for Nasopharyngeal Carcinoma Therapy

Figure 8

(a-b) Prussian blue staining in FR^- CNE-2 cells (a) and FR⁺ HNE-1 cells (b). (c–f) GFP expression in FR^- CNE-2 cells (c, d) and FR⁺ HNE-1 cells (e, f); (c/e) were under white light, and (d/f) were under blue excitation light. (g) The account of transfected cells (data was expressed as mean ± SD, , NS means nonsignificant and , and means significant and by -test). All cells were treated with FA-PEG-PEI@SPION-CDDP-TFPI-2 (Fe concentration = 5 ug/ml; 200x).

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