Rapid Detection and Identification of miRNAs by Surface-Enhanced Raman Spectroscopy Using Hollow Au Nanoflowers Substrates

Figure 1

UV-vis-NIR spectra of (a) Ag seeds, (b) HAuNFs, and (c) HAuNFs substrate. (d) SEM image of HAuNFs. Inset TEM image shows the internal structure of HAuNFs. Scale bars: 100 nm and 50 nm for the SEM image and TEM image, respectively. (e) EDS spectrum of HAuNFs. (f) SERS spectrum of (black curve) NBA and (red curve) HAuNFs colloidal dispersion mixed with NBA under 785 nm excitation. The integration time was 10 s and laser intensity was 5 mW.

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