Polymalic Acid Tritryptophan Copolymer Interacts with Lipid Membrane Resulting in Membrane Solubilization

Figure 4

Fluorescent confocal microscopy study of binding P/WWW to giant unilamellar vesicle (GUV). P/WWW was labeled with rhodamine (red) and the GUV was labeled with NBD (green) (GUV/copolymer weight ratio 8 : 1). The fluorescence of P/WWW overlays with that of GUV indicating the binding of P/WWW to the membrane of GUV.