Polymalic Acid Tritryptophan Copolymer Interacts with Lipid Membrane Resulting in Membrane Solubilization

Figure 5

Fluorescence resonance energy transfer (FRET) at pH 7.4 from NBD- phosphatidylethanolamine (NBD-PE) membrane to P/WWW/Rh (a) or P/LOEt/Rh (b). The arrow indicates the increase of FRET with the increase of concentration of P/WWW and P/LOEt/Rh copolymer. (c) The fluorescence emission spectrum of P/WWW/Rh and P/LOEt ranging from 560 nm to 750 nm at the same concentration.

(a)

(b)

(c)