Research Article
Preparation and Characterization of a Tumor-Targeting Dual-Image System Based on Iron Oxide Nanoparticles Functionalized with Folic Acid and Rhodamine
Figure 1
Schematic synthesis of amine-functionalized magnetite nanoparticles: (a) the surface of IONPs was modified with 2-AEP to form an amine-functionalized phosphonate monolayer, and (b) folic acid/rhodamine isothiocyanate were conjugated through the carbodiimide reaction, in order to obtain FA-IONPs-RITC.