Interaction of Solid Lipid Nanoparticles and Specific Proteins of the Corona Studied by Surface Plasmon Resonance

Figure 1

Simplified representation of the sensor surface to demonstrate the distinct layers of interest in the sensor surface and the correlation of the interactions that occurs in the sensor surface and the observed sensorgram. Roman numerals indicate (I) the protein layer after immobilization onto the thiol self-assembled monolayer, (II and III) SLN interaction with immobilized proteins at different times of the flow of SLN solutions, and (IV) the interaction of SLN-protein after restoration of buffer flow.