Research Article

Interaction of Solid Lipid Nanoparticles and Specific Proteins of the Corona Studied by Surface Plasmon Resonance

Table 2

(a) Mean diameter (-average), polydispersity index (PI), and zeta potential () of different formulations of solid lipid nanoparticles measured in deionized water. Data shown as mean ± standard deviation, .

SampleMean diameter (nm)PDI (mV)

SLN P188199 ± 30.10 ± 0.03−6.4 ± 0.9
SLN PVA161 ± 10.213 ± 0.006−1.5 ± 0.1
SLN CM154 ± 30.183 ± 0.00222 ± 1
SLN CL151 ± 30.18 ± 0.0213 ± 2
SLN P188+142 ± 10.154 ± 0.008−1.1 ± 0.1

(b) Mean diameter (-average), polydispersity index (PI), and zeta potential () of different formulations of solid lipid nanoparticles measured in PBS as diluting medium. Data shown as mean ± standard deviation, .

SampleMean diameter (nm)PDI (mV)

SLN P188207 ± 20.16 ± 0.02−2.8 ± 0.5
SLN PVA174 ± 10.237 ± 0.009−6.1 ± 0.1
SLN CM152.3 ± 0.30.175 ± 0.0070.7 ± 0.5
SLN CL146.5 ± 0.80.16 ± 0.012.2 ± 0.2
SLN P188+142 ± 10.16 ± 0.01−5.2 ± 0.4