Research Article

Fabrication of PLA-PEG Nanoparticles as Delivery Systems for Improved Stability and Controlled Release of Catechin

Table 1

Equations and parameters of mathematical models.

ModelEquationParameter definition

Zero order: concentration of drug
: zero-order constant
: time

First order: initial concentration
: concentration at time
: first-order constant
: time

Higuchi model: amount of drug released in time
: Higuchi constant
: time

Hixson-Crowell model: initial amount of drug
: remaining amount of drug at time
: Hixson-Crowell constant
: time

Korsmeyer-Peppas model: fraction of drug released at time
: Korsmeyer-Peppas constant
: time
: release exponent